Bio-identical Hormone & Peptide Specialists

Peptide Therapy:

RenewMe

Healthier Skin. Fuller Hair. Renewal From the Inside Out.

Aging doesn’t happen overnight — but the signals that drive it do change.

RenewMe is built around GHK-Cu therapy, a naturally occurring copper peptide that laboratory and animal studies link to skin repair and hair-follicle growth; clinical trials in people are still limited, but promising.12

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What Is GHK-Cu?

GHK-Cu is a naturally occurring copper peptide — a small but powerful messenger your body already produces.3

Its role is simple, but critical:
In laboratory and animal studies it promotes tissue repair, collagen production, and wound healing.45

Over time, those signals fade.

Blood levels of GHK fall with age — one review reports about 200 ng/mL at age 20 and 80 ng/mL by age 60, a drop of about 60%. Aging skin and hair often show:3

GHK-Cu is being studied as part of advanced peptide therapy for skin regeneration and hair, although well-designed clinical trials remain few.1

RenewMe supplements GHK-Cu under medical supervision.

Choose Your Renewal Path

RenewMe offers multiple GHK-Cu therapy options depending on whether you’re looking for full-body regenerative effects or targeted hair and scalp support.

Treatment Goals

Studies of topical GHK-Cu therapy products report firmer, more elastic skin with fewer fine lines and wrinkles; those studies did not use injections, and individual results vary.31

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The RenewMe Plan

Your Program Includes:

$275 per cycle

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How to Get Started

STEP 1

Book Your Assessment

$599 — One-Time

STEP 2

Unlock Membership

$279/month

STEP 3

Start Your RenewMe Specialty Treatment Plan

$275/cycle 

Add injectable GHK-Cu or topical Hair Foam to your personalized plan.

This program is typically cycled 2–4 times per year depending on your treatment plan.

Enhance your results

Pairs well with RenewMe

GHK-Cu works best when your underlying biology is working with it. These programs are commonly added alongside RenewMe for deeper, faster, and longer-lasting results.

Most paired
DefendMe
Thymosin Alpha-1
Immune Support

In experimental models of repair, excessive inflammation can delay healing and increase scarring.11 Your provider can discuss whether immune support fits your plan alongside GHK-Cu.

Reduces inflammation Immune resilience Better healing environment
Learn about DefendMe
Root cause
Hormone Health
Hormone Optimization
& Wellness

In women, lower estrogen after menopause is linked to thinner skin with less collagen and reduced elasticity.12 Hormone evaluation can identify contributing factors, and RenewMe can be considered alongside it.

Estrogen balance Hair & skin root cause Perimenopausal support
Learn about Hormone Health
Peak Performance
Growth Hormone
Peptide Program

In a trial in healthy young adults, growth hormone injections increased collagen synthesis in tendon and muscle.13 Your care team can advise whether combining a growth hormone peptide with GHK-Cu suits your goals.

Collagen synthesis Deep sleep repair Body composition
Learn about Peak Performance
Healing Peptides
Wolverine Stack
BPC-157 + TB-4

If joint pain, slow recovery, or chronic injury are part of the picture, the Wolverine Stack may be discussed — BPC-157 has aided tendon, ligament and muscle healing in rodent studies, though its efficacy has not yet been confirmed in humans. However, anecdotally, positive patient outcomes are noted.146

Joint & tendon repair Reduced inflammation Faster recovery
Learn about Healing Peptides

Not sure which combination is right for you? Your care team will build a personalized stack based on your labs and goals. Book your assessment to get started →

RenewMe · GHK-Cu Peptide Therapy

Your body's renewal signal fades with age

GHK-Cu is a copper peptide found naturally in the body and studied for tissue repair and collagen production. One review reports plasma GHK falling from about 200 ng/mL at age 20 to 80 ng/mL by age 60.3

Natural GHK-Cu level Illustrative reference line (not a clinical threshold)
Illustrative curve only: plasma GHK is reported at about 200 ng/mL at age 20 and 80 ng/mL at age 60; values for other decades and any symptom threshold are not established.
Peak level
100%
in your 20s
By your 60s
~40%
remaining
Total decline
60%
lost by your 60s
Visible aging changes
Vary
Timing differs from person to person

Curve is illustrative: a published review reports plasma GHK declining with age, from about 200 ng/mL at 20 to 80 ng/mL at 60; intermediate values are not measured data. Individual levels vary.3

RenewMe adds GHK-Cu under medical supervision — ask whether it fits your goals.

Book your assessment →

What You Need to Know

Because GHK-Cu therapy contains copper, we carefully monitor your copper–zinc balance throughout treatment.

  • Zinc is taken alongside therapy to maintain balance
  • Bloodwork is completed before each new cycle, as recommended by your provider
  • Once stable, monitoring is reduced to annually
  • If levels rise, therapy is paused and adjusted safely

Safety Notes:

  • Not recommended during pregnancy or breastfeeding
  • Always disclose medications and supplements
  • Safety data for injected GHK-Cu in people are limited — report any side effects6
  • Mild redness or swelling at the injection site may occur; tell your provider if it persists
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How is GHK-Cu therapy different from topical skincare products?

Many skincare ingredients act mainly at the skin surface. In laboratory and animal studies, GHK-Cu influences deeper repair processes such as collagen and extracellular matrix production; long-term regenerative benefits in people have not yet been established.57

GHK-Cu has a long history of use in skin-care products, but safety data for injected GHK-Cu in people are limited. Because it contains copper, your provider monitors your copper–zinc balance as a precaution.156

Response times vary and have not yet been established for GHK-Cu therapy; your provider will review your progress at follow-up visits.

Injectable GHK-Cu is delivered systemically, while topical applications are applied to specific areas like the scalp. The best option depends on your goals and treatment plan.

Possibly. Copper peptides have enlarged hair follicles in laboratory and animal studies, and in one small randomized trial a GHK-containing complex increased hair counts in men with pattern hair loss; GHK-Cu itself has not yet been proven to treat hair thinning. Anecdotally, though, patients do report positive outcomes.168

Yes. Many patients combine GHK-Cu therapy with other treatments focused on longevity or immune support to create a more comprehensive approach to health optimization.

RenewMe FAQs

Ready to Renew Your Skin and Hair?

Aging is inevitable — but how your body responds to it isn’t.

Find out whether GHK-Cu therapy fits your skin and hair goals.

GHK-Cu & RenewMe in Conshohocken & Greater Philadelphia

The RenewMe program is prescribed and monitored from our Conshohocken clinic, in Montgomery County just outside Philadelphia. Bloodwork is drawn locally and visits are available in person or by telehealth across Pennsylvania.

YoungerMeMD · 125 East Elm Street, Suite 201, Conshohocken, PA 19428 · (215) 892-1230

Frequently Asked Questions

What is GHK-Cu?
GHK-Cu is a naturally occurring copper peptide found in human plasma; in laboratory and animal studies it promotes tissue repair and collagen production.35
What is the difference between the injectable and topical options?
Injectable GHK-Cu is delivered systemically, while the topical hair foam is applied directly to the scalp without a systemic approach.
What improvements do patients tend to notice?
Studies of topical GHK-Cu skin products have reported improved firmness and elasticity and fewer fine lines and wrinkles; those studies did not use injections, and individual results vary.31
Why is RenewMe sometimes paired with hormone or immune programs?
Excessive inflammation can delay healing in experimental models, and lower estrogen after menopause is linked to thinner skin, so your provider may evaluate these factors alongside RenewMe.1112

References

  1. Mokhtar J, et al. The Regenerative Potential of GHK-Cu in Aesthetic Medicine. Aesthet Surg J 2026. PMID 42619529 · doi:10.1093/asj/sjag169↩
  2. Pickart L. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed 2008. PMID 18644225 · doi:10.1163/156856208784909435↩
  3. Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int 2015. PMID 26236730 · PMC4508379 · doi:10.1155/2015/648108↩
  4. Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci 2018. PMID 29986520 · PMC6073405 · doi:10.3390/ijms19071987↩
  5. Maquart FX, et al. In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds. J Clin Invest 1993. PMID 8227353 · PMC288419 · doi:10.1172/JCI116842↩
  6. Mayfield CK, et al. Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians. Am J Sports Med 2026. PMID 41476424 · doi:10.1177/03635465251357593↩
  7. Maquart FX, et al. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Lett 1988. PMID 3169264 · doi:10.1016/0014-5793(88)80509-x↩
  8. Uno H, Kurata S. Chemical agents and peptides affect hair growth. J Invest Dermatol 1993. PMID 8326148 · doi:10.1111/1523-1747.ep12363275↩
  9. Wang X, et al. GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. Wound Repair Regen 2017. PMID 28370978 · doi:10.1111/wrr.12520↩
  10. Pyo HK, et al. The effect of tripeptide-copper complex on human hair growth in vitro. Arch Pharm Res 2007. PMID 17703734 · doi:10.1007/BF02978833↩
  11. Eming SA, Krieg T, Davidson JM. Inflammation in wound repair: molecular and cellular mechanisms. J Invest Dermatol 2007. PMID 17299434 · doi:10.1038/sj.jid.5700701↩
  12. Thornton MJ. Estrogens and aging skin. Dermatoendocrinol 2013. PMID 24194966 · PMC3772914 · doi:10.4161/derm.23872↩
  13. Doessing S, et al. Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis. J Physiol 2010. PMID 19933753 · PMC2821728 · doi:10.1113/jphysiol.2009.179325↩
  14. Gwyer D, Wragg NM, Wilson SL. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell Tissue Res 2019. PMID 30915550 · doi:10.1007/s00441-019-03016-8↩
  15. Pickart L, Vasquez-Soltero JM, Margolina A. The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health. Oxid Med Cell Longev 2012. PMID 22666519 · PMC3359723 · doi:10.1155/2012/324832↩
  16. Lee WJ, et al. Efficacy of a Complex of 5-Aminolevulinic Acid and Glycyl-Histidyl-Lysine Peptide on Hair Growth. Ann Dermatol 2016. PMID 27489425 · PMC4969472 · doi:10.5021/ad.2016.28.4.438↩
Medically reviewed by Kenneth Varano, D.O., Pennsylvania osteopathic physician license OS009028L (Pennsylvania State Board of Osteopathic Medicine) · Last reviewed Medical Director, YoungerMeMD · Board certified in Integrative Medicine (ABOIM) and Family Practice, and an Advanced Fellow in Anti-Aging, Functional and Nutritional Medicine (A4M).
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      No provocation agent required. A urine test that checks for toxic metals standard labs do not routinely test for.

      Identifies gluten sensitivity, intestinal permeability (leaky gut), and wheat-related immune reactivity – distinct from standard celiac testing.

      DNA Based stool test detecting pathogens, bacterial imbalances, parasites, and digestive markers – a comprehensive gut microbiome assessment.

      Non-invasive carotid artery ultrasound measuring arterial wall thickness – a direct look at your cardiovascular age.

      Cardio Res-Q cardiac risk panel – inflammation markers and cardiovascular biomarkers beyond standard labs.

      Estimates nutrient-related markers from DNA methylation with an at-home finger-prick kit. Not a diagnostic test; flagged results are confirmed with standard blood work.

      Full Sex hormone, thyroid and adrenal picture. Identifies imbalances that affect energy, recovery, cognition, and peptide response.

      Advanced testing for immune reactions to wheat, gluten, and intestinal permeability.

      What It Evaluates

      Heavy metals like mercury, lead, cadmium, arsenic, and aluminum can cause:

      Conditions We Identify